The Sector Leadership Index™: Tiering Law Firms by Life Sciences Sector Strength

Law firms frequently describe themselves as “Life Sciences firms” to emphasize desired immersion in the Life Sciences sector. Clients, however, experience meaningful differences in industry fluency, depth, investment, and relevance from one firm to the next.

To bring rigor and clarity to this conversation, I developed the Sector Leadership Index™ (SLI)—a quantitative framework evaluating 265 U.S. and international law firms based on their demonstrated strength in the Life Sciences sector. The SLI reflects how sophisticated Life Sciences clients actually view the market.

Global Life Sciences elite

With that, we celebrate The Global Life Sciences Elite. These 18 firms represent the most advanced Life Sciences platforms in the market. They combine scale, depth, cross-border capability and sustained investment across multiple Life Sciences subsectors. For many sophisticated clients, these firms define the reference standard:

  • Arnold & Porter

  • Bartlit Beck

  • Bookoff McAndrews

  • CMS Cameron McKenna Nabarro Olswang

  • Cooley

  • Covington & Burling

  • Fenwick

  • Freshfields

  • Goodwin

  • Hogan Lovells

  • Hyman, Phelps & McNamara

  • King & Spalding

  • Latham & Watkins

  • McDermott Will & Schulte

  • Nelson Mullins Riley & Scarborough

  • Sidley Austin

  • WilmerHale

  • Wilson Sonsini Goodrich & Rosati

global life sciences MARKET leaders

Market Leaders are highly credible, highly visible firms with deep strength in priority Life Sciences subsectors. They compete consistently for complex, high-value matters and often dominate specific segments of the market. These 78 firms include:

  • A&O Shearman

  • Allen Matkins

  • Alston & Bird

  • ArentFox Schiff

  • Baker Botts

  • Baker Donelson Bearman Caldwell & Berkowitz

  • Baker McKenzie

  • Ballard Spahr

  • Bass Berry & Sims

  • Benesch

  • Bird & Bird

  • Brown Rudnick

  • Butler Snow

  • Clifford Chance

  • Cozen O'Connor

  • Crowell & Moring

  • Debevoise & Plimpton

  • Dechert

  • Dentons

  • DLA Piper

  • Duane Morris

  • Epstein Becker & Green

  • Faegre Drinker Biddle & Reath

  • Finnegan Henderson Farabow Garrett & Dunner

  • Fish & Richardson

  • Foley & Lardner

  • Foley Hoag

  • Fragomen Del Rey Bernsen & Loewy

  • Fried Frank Harris Shriver & Jacobson

  • Gibson Dunn & Crutcher

  • Greenberg Traurig

  • Haynes and Boone

  • Holland & Knight

  • Honigman

  • Hunton Andrews Kurth

  • Ice Miller

  • Jackson Lewis

  • Keller and Heckman

  • Kilpatrick Townsend & Stockton

  • Kirkland & Ellis

  • Knobbe Martens

  • Lathrop GPM

  • Linklaters

  • Littler Mendelson

  • Loeb & Loeb

  • Manatt Phelps & Phillips

  • McGuireWoods

  • Michael Best & Friedrich

  • Milbank

  • Mintz

  • Morgan Lewis & Bockius

  • Morrison Foerster

  • Nixon Peabody

  • Norton Rose Fulbright

  • Ogletree Deakins Nash Smoak & Stewart

  • O'Melveny & Myers

  • Orrick Herrington & Sutcliffe

  • Paul Hastings

  • Paul Weiss Rifkind Wharton & Garrison

  • Perkins Coie

  • Pillsbury

  • Quinn Emanuel Urquhart & Sullivan

  • Rakoczy Molino Mazzochi Siwik

  • Reed Smith

  • Ropes & Gray

  • Saul Ewing

  • Sheppard Mullin Richter & Hampton

  • Shook Hardy & Bacon

  • Simpson Thacher & Bartlett

  • Skadden Arps Slate Meagher & Flom  & Affiliates

  • Sterne Kessler Goldstein & Fox

  • Taft

  • Taylor Wessing

  • Troutman Pepper Locke

  • Tucker Ellis

  • White & Case

  • Winston & Strawn

  • Wolf Greenfield & Sacks

Life Sciences Growth Platforms

These 89 firms have made intentional investments in Life Sciences and are actively expanding their sector footprint. Many are ascending rapidly through lateral hiring, client wins, and increased market visibility.

  • Akerman

  • Akin

  • Arnall Golden Gregory

  • Barnes & Thornburg

  • Blank Rome

  • Bradley Arant Boult Cummings

  • Bricker Graydon

  • Buchalter A Professional Corporation

  • Buchanan Ingersoll & Rooney

  • Burr & Forman

  • Carlson Caspers

  • Chapman and Cutler

  • Choate Hall & Stewart

  • Cleary Gottlieb Steen & Hamilton

  • Cole Scott & Kissane

  • Davis Wright Tremaine

  • Day Pitney

  • Dorsey & Whitney

  • Dykema Gossett

  • Fieldfisher

  • Fisher Phillips

  • Fitch Even Tabin & Flannery

  • Fox Rothschild

  • Fredrikson & Byron

  • Frier Levitt

  • Frost Brown Todd

  • Goldberg Segalla

  • Goldman Ismail Tomaselli Brennan & Baum

  • Goulston & Storrs

  • Groombridge Wu Baughman & Stone

  • Gunderson Dettmer Stough Villeneuve Franklin & Hachigian

  • Hamilton Brook Smith & Reynolds

  • Hanson Bridgett

  • Harris Beach Murtha

  • Hooper Lundy Bookman

  • Hughes Hubbard & Reed

  • Husch Blackwell

  • Irell & Manella

  • Irwin Fritchie Urquhart & Moore

  • Jackson Kelly

  • Jackson Walker

  • Jones Day

  • Katten

  • Kelley Drye & Warren

  • Kobre & Kim

  • Kutak Rock

  • Lewis Brisbois Bisgaard & Smith

  • Leydig Voit & Mayer

  • Lowenstein Sandler

  • Marshall Gerstein & Borun

  • Mayer Brown

  • Maynard Nexsen

  • McAndrews Held & Malloy

  • McCarter & English

  • McDonnell Boehnen Hulbert & Berghoff

  • McNeill

  • Miles & Stockbridge

  • Moore & Van Allen

  • Morgan & Morgan

  • Munger Tolles & Olson

  • Parker Poe Adams & Bernstein

  • Patterson Belknap Webb & Tyler

  • Phelps Dunbar

  • Proskauer Rose

  • Pryor Cashman

  • Quarles & Brady

  • Robins Kaplan

  • Robinson+Cole

  • Rothwell Figg

  • Seed Intellectual Property Law Group

  • Seyfarth Shaw

  • Smith Anderson

  • Snell & Wilmer

  • Spencer Fane

  • Squire Patton Boggs

  • Steptoe & Johnson

  • Steptoe

  • Stinson

  • Susman Godfrey

  • Thompson Coburn

  • Thompson Hine

  • Venable

  • Vinson & Elkins

  • Weil Gotshal & Manges

  • Wiley

  • Williams & Connolly

  • Willkie Farr & Gallagher

  • Wilson Elser Moskowitz Edelman & Dicker

  • Womble Bond Dickinson

  • Zuckerman Spaeder

The Seven Elements of the Sector Leadership Index™

The SLI measures Life Sciences sector strength across seven weighted elements. Together, they capture not just reputation, but execution.

  1. Market Presence & Visibility
    Evidence of sustained Life Sciences positioning in rankings, media, and thought leadership.

  2. Subsector Breadth & Depth
    Demonstrated strength across priority Life Sciences subsectors (e.g., biotech, pharma, medical devices, diagnostics, digital health).

  3. Talent & Headcount Commitment
    Depth of partner- and associate-level investment dedicated to Life Sciences work.

  4. Client Engagement & Relevance
    Evidence of active representation of Life Sciences companies, investors, and institutions.

  5. Investment & Infrastructure
    Formal sector teams, leadership roles, budgets, and operational support.

  6. Content & Thought Leadership
    Quality, consistency, and sophistication of Life Sciences–specific insights and commentary.

  7. Go-to-Market Discipline
    Evidence of intentional sector strategy rather than incidental participation.

Important Disclaimers (Please Read)

  • These tiers reflect relative Life Sciences sector strength, not overall firm quality, legal excellence, or prestige.

  • Firms appear in different tiers due to strategic focus, scale, and investment choices, not merit judgments.

  • Regional and international firms are evaluated within appropriate competitive contexts, not forced into false equivalencies.

  • The SLI is designed to mirror client perception, not internal firm narratives.

Methodology Note:
The Sector Leadership Index™ (SLI) evaluates law firms based on demonstrated Life Sciences sector strength across seven weighted dimensions, including market presence, subsector depth, talent investment, client engagement, infrastructure, thought leadership, and go-to-market discipline.

The SLI measures sector maturity and credibility, not overall firm quality or legal capability. Firms are grouped into tiers to reflect relative positioning within the Life Sciences market.

James J. Stapleton is the Managing Principal of Client Sciences and the creator of the Sector Leadership Index and the Client Performance Index. He challenges the way the legal market evaluates expertise, arguing that clients use industry sector expertise as a primary lens into their law firm selection.

After more than three decades building AmLaw 100 law firms and global professional services firms PwC and Arthur Andersen—and advising on over 7,500 law firm/client transitions—Mr. Stapleton now helps law firms communicate their industry credibility and aids clients in cutting through marketing claims to identify firms with genuine sector immersion.

Mr. Stapleton can be reached at 408-440-7660 or james.stapleton@clientsciences.com.

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The Client Performance Index™: Measuring How Life Sciences Clients Experience Law Firms

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Introducing the Client Performance Index™ (CPI):